[reverett123]

On the personal level, nothing hits me harder than MSG. It blocks my meds completely for up to six hours and I do mean completely. Even triple doses don't do anything. I can't walk. I can barely move my arms. In short, it is a real bummer. Plus, it kills nrurons.

So, I was more than a little interested in this study from earlier this year-


1: Pak J Biol Sci. 2009 Feb 1;12(3):201-12.

Neuroprotective evaluation of extract of ginger (Zingiber officinale) root in
monosodium glutamate-induced toxicity in different brain areas male albino rats.

Waggas AM.

Department of Zoology, Faculty of Girls Education, Scientific Departments,
Jeddah, Saudi Arabia.

In this study, the neuroprotective effect of the extract of ginger (Zingiber
officinale) was investigated against MSG-induced neurotoxicity of male albino
rat. The daily dose (4 mg kg(-1) b.wt.) i.p. injection of pure monosodium
glutamate (MSG) for 30 days and subsequent withdrawal caused a significant
decrease in epinephrine (E), norepinephrine (NE), dopamine (DA) and serotonin
(5-HT) content all tested areas (cerebellum, brainstem, striatum, cerebral
cortex, hypothalamus and hippocampus) at most of the time intervals studied. This
is may be due to activation of glutamate receptors, which led to increased the
intracellular concentration of Ca(+2) ions, so the release of neurotransmitters
is increased and the content of monoamines is decreased. After the withdrawal,
the decrease in monoamines levels remained in striatum, cerebral cortex and
hypothalamus, this may be due to the region specific effect of monosodium
glutamate whereas, daily dose (100 mg kg(-1) b.wt.) i.p., injection of Ginger
(Zingiber officinale) root extract for 30 days and subsequent withdrawal caused a
significant increased in epinephrine (E), norepinephrine (NE), dopamine (DA) and
serotonin (5-HT) content all tested areas at most of the time intervals studied.
This is may be due to inhibition of 5HT-3-receptor effects at the same time the
extract blockade of Ca(+2) channel, as result the release of neurotransmitter is
decreased and the content is increased. After the extract withdrawal, the
increase in monoamine levels remained in brainstem, striatum and hippocampus,
this may be due to the region specific effect of the extract. The coadminisration
of monosodium glutamate and ginger root extract caused increased in monoamine
content in most of the tested brain areas at different time intervals. This is
may be due to partly attributable to an antagonistic action of ginger root
extracts on monosodium glutamate effect, so the monoamines content was increased.
From these results, we can say that the ginger extract has a neuroprotective role
against monosodium glutamate toxicity effect.


PMID: 19579948 [PubMed - indexed for MEDLINE]

[mrsD]

MSG is hard on chronic pain too. It is murder for Peripheral neuropathy.

[Chemar]

http://www.naturalnews.com/026973_MSG_food_foods.html



MSG has very serious impact on my son's TS tics and it really angers me that food manufacturers are calling it all this other stuff, IMHO deceptively