Autoimmune Diseases For Hashimoto’s thyroiditis (underactive thyroid), Graves’ disease (overactive thyroid), Lupus, Crohn's disease, all types of arthritis, and all other autoimmune diseases. [Multiple sclerosis (MS) and Myasthenia Gravis (MG) have their own forums below.]


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Old 05-12-2009, 07:21 PM #1
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Hi. I am also in the MG forum.

I have just been diagnosed with perpheral neuropathy in my legs. I have numbness in my calves, ankles, and feet. My EMG was abnormal but they did another test with about 10 Blood pressure cuffs...and it was normal...but..my lovely toes turn a lovely shade of blue when I sit too long .....and I have been stumbling and falling...my ankel turns easy... I do not have diabetes or a family hx of it..and I do not drink or smoke....

However, I have had a hx of graves disease...but it is resolved..(or I was told it was resolved)...because all of my thyroid levels are all within normal limits....except for my thyroid antibiodies are high...so now...I am scheduled for a thyroid uptake scan and a thyroid ultrasound....

So my question....does all this tie together.....I was diagnosed with MG....but my neuro thinks the neuropathy and thyroid problems are a separate issue....I am only 37...and healthy...(i thought...)

Has anyone had these symptoms?? What could this be?? neuropathy and thyroid antibiodies.....
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Old 05-15-2009, 10:07 PM #2
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Thyroid autoantibodies this could be adding to your problems.

You need to check your Total T4, Total T3 levels and maybe Reverse T3 levels. TSH by itself is a joke of a test.

What are your autoantibodies at? levels and reference ranges?

Also Peripheral neuropathy can be caused by B12 deficiency. I would Check B12, Red Cell Folate and Iron Studies.

The range i have here in australia is 200-800. Anything BELOW 500 is DEFICIENCY remember that dont listen to your doctor. It matters what's inside your cells not in your blood.

Peripheral neuropathy also can be caused by degeneration of the myelin sheaths, the insulation around the axons.

Vitamin B12 is essential to cells because it's needed to assist folate in making DNA (deoxyribonucleic acid) and RNA (ribonucleic acid), which carry and transmit genetic information for every living cell. This information tells a cell how to function and must be passed along each time a cell divides.

Rapidly dividing cells need a continuous supply of vitamin B12 and folate. Vitamin B12 plays a central role in folate metabolism. It releases free folate from its bound form so it can be absorbed, and it helps in the transportation and storage of folate.

A deficiency of vitamin B12 can create a folate deficiency even when dietary intake of folate is adequate. That is why a deficiency of either vitamin causes a similar type of anemia.

Vitamin B12 functions in the production of a material called myelin, which covers and protects nerve fibers. Without enough B12, the myelin sheath does not form properly or stay healthy. As a result, nerve transmission suffers, and people experience irreversible nerve damage.

I would try to get the Methylcobalamin form of Vitamin B12 as this has been used to regenerate nerves in people with nerve related diseases.

Finally An Essential Fatty Acid supplement would be very helpful. Containing Omega 3, 6 and 9. Omegas help keep the neurones which connect up to the brain in good shape.
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Old 05-16-2009, 12:41 AM #3
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Quote:
Originally Posted by cricket001 View Post
Hi. I am also in the MG forum.

I have just been diagnosed with perpheral neuropathy in my legs. I have numbness in my calves, ankles, and feet. My EMG was abnormal but they did another test with about 10 Blood pressure cuffs...and it was normal...but..my lovely toes turn a lovely shade of blue when I sit too long .....and I have been stumbling and falling...my ankel turns easy... I do not have diabetes or a family hx of it..and I do not drink or smoke....

However, I have had a hx of graves disease...but it is resolved..(or I was told it was resolved)...because all of my thyroid levels are all within normal limits....except for my thyroid antibiodies are high...so now...I am scheduled for a thyroid uptake scan and a thyroid ultrasound....

So my question....does all this tie together.....I was diagnosed with MG....but my neuro thinks the neuropathy and thyroid problems are a separate issue....I am only 37...and healthy...(i thought...)

Has anyone had these symptoms?? What could this be?? neuropathy and thyroid antibiodies.....
Hi Cricket... You can come to our PN forum and post there too.

But I have an observation for you. Some people with autoimmune issues have Gluten intolerance/Celiac. They may have thyroid issues as well. I recall one poster who had PN which resolved on the gluten free diet.
So you might want to visit the gluten forum here and read the stickies.

People who are reacting to the gluten peptide (gliadin) may have a damaged lining in the intestine where nutrients are normally absorbed. This leads to low levels of some nutrients like B12 especially which then result in neurological deficits.
This is called malabsorption. And it can be corrected by avoiding gluten containing foods, so the intestine can heal.

So please take a look. Glenntaj and Darlindeb both post on both forums here.
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Old 05-19-2009, 11:11 AM #4
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Default Checking thyroid levels.....

Don't just 'check' the basic T-3 and T-4 levels, there are free T3 and 4's and also...more importantly the immune/autoimmune T3 and T4's. The latter is what should be checked out thoroughly! and monitored often. When the thyroid goes whacky, other endocrine glands help take up some of the slack, but they too can have too much asked of them.
Check out this site: http://www.endocrineweb.com/
It will tell you more than enough to deal with things, I hope. Basic info will help you make better informed decisions...
All the best! - j
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