NeuroTalk Support Groups - diet thread.....

Hi,

After one of my friends told me that she has lost weight on the green coffee bean extract, I found some research. In this and similar studies, people have lost weight on the Green Coffee Bean Extract.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267522/

Randomized, double-blind, placebo-controlled, linear dose, crossover study to evaluate the efficacy and safety of a green coffee bean extract in overweight subjects

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Significant reductions were observed in body weight (−8.04 ± 2.31 kg), body mass index (−2.92 ± 0.85 kg/m2), and percent body fat (−4.44% ± 2.00%), as well as a small decrease in heart rate (−2.56 ± 2.85 beats per minute), but with no significant changes to diet over the course of the study. Importantly, the decreases occurred when subjects were taking GCA. Body mass index for six subjects shifted from preobesity to the normal weight range (<25.00 kg/m2).

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This was a randomized, double-blind,[B] 22-week study

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It must be said that the daily dose of GCA in this study ranged from 700 to 1050 mg

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There have been some recent articles indicating that chlorogenic acid and its metabolite, caffeic acid, inhibit amylase at mM concentrations in vitro which, if it occurred in the gastrointestinal tract in vivo, would inhibit sugar absorption from starch consumption and thus decrease caloric input

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The subjects averaged slightly over an 8 kg weight loss which was more than 10% of the body weight. For our study 10 of 16 subjects showed at least a 10% weight loss; five of the remaining six showed at least 5% weight loss; and the last individual showed a 4% weight loss. The most remarkable result was the fact that all 16 of the subjects were classified as overweight at the beginning of the study and at the end six of the subjects were now in the normal BMI category, ie, a normal weight for their height.

Translated into my understanding:
During a 22 week study, people were given 700 to 1050 mgs of the Green Coffee Bean Extract. There were 16 people in the study. All lost weight. The average weight loss was 8 kgs (17.6 pounds).

Here is a link to the exact product used in the study: (Source Naturals)
http://www.sourcenaturals.com/products/GP1819/

M