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The ketogenic diet may have mood-stabilizing properties.

 
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Old 02-18-2007, 03:26 AM #1
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Default The ketogenic diet may have mood-stabilizing properties.
Med Hypotheses. 2001 Dec;57(6):724-6.
The ketogenic diet may have mood-stabilizing properties.

El-Mallakh RS,
Paskitti ME.
Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Kentucky 40292, USA.

Quote:
The ketogenic diet, originally introduced in the 1920s, has been undergoing a recent resurgence as an adjunctive treatment for refractory epilepsy, particularly in children. In this difficult-to-treat population, the diet exhibits remarkable efficacy with two-thirds showing significant reduction in seizure frequency and one-third becoming nearly seizure-free.

There are several reasons to suspect that the ketogenic diet may also have utility as a mood stabilizer in bipolar illness. These include the observation that several anticonvulsant interventions may improve outcome in mood disorders.

Furthermore, beneficial changes in brain-energy profile are noted in subjects on the ketogenic diet. This is important since global cerebral hypometabolism is a characteristic of the brains of depressed or manic individuals.

Finally, the extracellular changes that occur in ketosis would be expected to decrease intracellular sodium concentrations, a common property of all effective mood stabilizers.

Trials of the ketogenic diet in relapse prevention of bipolar mood episodes are warranted.
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Old 02-18-2007, 11:24 AM #2
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I have not goggle ketogenic but is that a high protein diet?
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I will not give up in this weight loss journey, nor this need to be AF. 3-19-13=156, 6-7-13=139, 8-19-13=149, 11-12-13=140, 6-28-14=157, 7-24-14=149, 9-24-14=144, 1-12-15=164, 2-28-15=149, 4-21-15=143, 6-26-15=138.5, 7-22-15=146, 8-24-15=151, 9-15-15=145, 11-1-15=137, 11-29-15=143, 1-4-16=152, 1-26-16=144, 2-24-16=150, 8-15-16=163, 1-4-17=169, 9-20-17=174, 11-17-17=185.6, 3-22-18=167.9, 8-31-18= 176.3, 3-6-19=190.8 5-30-20=176, 1-4-21=202, 10-4-21= 200.8,12-10-21=186, 3-26-22=180.3, 7-30-22=188, 10-15-22=180.9,
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Old 02-18-2007, 03:18 PM #3
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Hi,
It's a high fat diet. 80-90% of the calories are from fat. Cheese cake is allowed I think.
I would not try to reach ketosis without a doctor.
Mari

http://www.epilepsy.org.uk/info/ketogenic.html
Quote:
The ketogenic diet is a high fat, adequate protein, low carbohydrate diet designed to mimic many of the biochemical changes associated with prolonged starvation.

http://www.ttuhsc.edu/som/FamMed/dietcomp.jpg -- pie chart of the diet

http://www.ttuhsc.edu/som/fammed/ketogenic.html
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Old 02-18-2007, 06:09 PM #4
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like eskimos!
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Hattie the black and white one wrestling with hazel, calico. lost hattie to cancer.....
Happiness is a decision....

150mg of lamictal 2x a day
haldol 5mg 2x a day
1mg of cogentin 2x a day
klonipin , 1mg at night


I will not give up in this weight loss journey, nor this need to be AF. 3-19-13=156, 6-7-13=139, 8-19-13=149, 11-12-13=140, 6-28-14=157, 7-24-14=149, 9-24-14=144, 1-12-15=164, 2-28-15=149, 4-21-15=143, 6-26-15=138.5, 7-22-15=146, 8-24-15=151, 9-15-15=145, 11-1-15=137, 11-29-15=143, 1-4-16=152, 1-26-16=144, 2-24-16=150, 8-15-16=163, 1-4-17=169, 9-20-17=174, 11-17-17=185.6, 3-22-18=167.9, 8-31-18= 176.3, 3-6-19=190.8 5-30-20=176, 1-4-21=202, 10-4-21= 200.8,12-10-21=186, 3-26-22=180.3, 7-30-22=188, 10-15-22=180.9,
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Old 01-16-2011, 03:15 PM #5
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Quote:
Originally Posted by bizi View Post
like eskimos!
Hi, Bizi. I think perhaps the Inuit and others eating traditional food diets, just might have the right idea. I really liked your post. Thank you.

There is a lovely post at the blog connected to the Failsafe Diet site at wordpress about on GABA. The blog is called "autoimmunethyroid" at wordpress.
Last edited by S. J.; 01-16-2011 at 04:35 PM. Reason: added information
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Old 01-16-2011, 03:22 PM #6
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Chocolate was everything that came to my mind...
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Old 01-17-2011, 07:03 AM #7
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Default still looking for better science
Hi,
Every six months or so, I check google scholar for updated publications about this diet for bipolar. I get nothing.

Intuitively, it seems that the ketogenic diet would work on mood, anxiety, and so on.

I'm willing to bet that we will see some good science at some point --especially as the diet is being readapted into the epilepsy community.

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Old 01-22-2011, 04:25 PM #8
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Haven't been here in awhile.
Had surgery (long story).
Anyway, is the ketogenic diet similar to the paleo diet (several books out these days)?
My doc put me on something similar...
Lots of veggies....lean meat, fish etc.
Nuts, seeds, some fruit
No sugar, dairy or grains.
Anyway, I'm losing a little weight after lots of frustration.
It's still a tad slow, but more consistent and I feel well.
The word "ketogenic" reminds me of the Atkinds stuff.
Atkins always seemed "fatty" to me and this isn't.
You havning luck on it Mari? Did I see a super slender photo of Bizi?
Way to go folks!
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Old 01-22-2011, 06:07 PM #9
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Hi Vowel Lady

just want to welcome you back.

sorry you had to have surgery - hope everything went smoothly and that you're recovered. if you're still in the recovery bit, well then let me send you good energy for that.

(((hugs)))

~ waves ~
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Old 01-22-2011, 06:18 PM #10
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Default ketogenic diet -- 80-90% of the calories from fat
Quote:
Originally Posted by Vowel Lady View Post
Haven't been here in awhile.
Had surgery (long story).
Anyway, is the ketogenic diet similar to the paleo diet (several books out these days)?
Dear Vowel Lady,

The ketogenic diet helps control seizures for some people with epilepsy. It is a high fat diet -- 80-90% of the calories from fat.
Some researchers think it might work for bipolar, but we have no research on it yet -- no drug companies to pay for it.
While we wait for the research, some folks with bipolar might benefit from a low-ish carb diet and good oils.

Right now I am doing Weight Watchers. They emphasize lots of veggies, fruit, and good lean protein.

Bizi recently started doing the Paleolithic diet.


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