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Old 05-31-2014, 12:13 AM #31
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Donna,

That is great that you and Derrick have meds that work for you.

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Old 05-31-2014, 03:13 AM #32
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Quote:
Originally Posted by Mari View Post
Steve,


Call that pharmacist in the capitol back to talk about the panic attack with the Chlorpheniramine Maleate. Anxiety is listed as a side effect.
  • Perhaps it interferes with other medications.
  • Perhaps you can benefit from a smaller dose.
  • Perhaps you could take it every other day.
  • Maybe you could time it in such a way as it has a half life of 21-27 half life.
  • . . which is why I think you could ask if it could help you every other day.


This site suggests not to take it with caffeine, aspirin, tylenol, or Topamax
http://www.drugs.com/drug-interactio...&generic_only=

It seems to have some SSRI and/ or SNRI properties -- the pharmacist would know more.


++++
Someone here will correct me if I am wrong as I have no experience with these meds.

Mari
Thank you Mari. That helps me. I thought that I was having problems with the chlorpheniramine. Panic,or slight fear are very difficult to work through. My current medications help.

I've read through some of the reports here,and I think that I might try Zyrtec for allergy rhinitis,and asthma. I don't have asthma,but I have a drip that probably sounds like asthma. BF
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Old 05-31-2014, 03:42 AM #33
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Originally Posted by waves View Post
Oh Steve, I do apologize. I somehow missed this earlier.

Durahist-D is dexchlorpheniramine. It is the "active" isomer of chlorpheniramine. Molecularly, Durahist has the interaction potential you were concerned about chlorpheniramine.

If you didn't see a panic problem with the Durahist-D, I'd have to suggest that the worsening you saw in the panic disorder was more than likely coincidence. I'd say, if the Durahist worked for you, then try the chlorpheniramine again.

Another possibility is how often did you take the Durahist? Every four hours? You should get a formulation of chlorpheniramine that is to be taken at the same intervals... dosages affect peak drug levels. An extended release version could produce different side effects than an immediate release, and vice versa.

Chlorpheniramine used to be available in immediate release,(4-hour dosing, intermedieate (8-hour) and extended (12-hour) dosing. For the 8- and 12-hour release versions, you might have to get a hold of Chlor-Trimeton brand and I don't know if that's available still. The 4-hour version is standard and is available in all generics.
Hey Waves. Thank you. I just turned on a lamp to see what they call this Durahist D Caplet Pro. I took it twice daily.

The generic says it's (P-EPHED HCL/Dexchlorphen/scop) They phased it out,but this worked for me. If I could get the right measurements of the meds in this anti allergy pill it would be great,but it would probably be impossible to get the info. I'm not even sure if it would be legal.

I thank everyone for their information,and help for my allergy treatments. I've fallen through the cracks of the Allergy Treatment doctors,and my insurance at the time caused me to suffer by eliminating my shots that where definitely helping. I wonder how many people have the same experiences? BF and a extra Hug
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Old 05-31-2014, 03:50 AM #34
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Originally Posted by mrsD View Post
All the pheniramine drugs are second generation and have some drowiness and other CNS effects. They can affect the brain because histamine is a signaling neurotransmitter in the brain, to release other neurotransmitters. Also some antihistamines like Benadryl have actions on motor neurons...and are used sometimes for side effects of movement disorders caused by other drugs.

The newer one like Allegra (a metabolite of the old Seldane which was taken off the market), have much less CNS effects if any. Claritin is a poor antihistamine all around so I don't recommend it. Zyrtec has retained some of the characteristics of
its chemical parent Atarax, and has some CNS effects, but not as many as the Atarax has. Both Allegra and Zyrtec are OTC now.

The new allergy nose ointments, block the pollen before it gets into your nose at all...
example:
http://www.amazon.com/Chloraseptic-A.../dp/B001BNQVC6
This is drug free and works well for most.
Thank you MrsD. That's helpful,and interesting information. It's a little difficult to understand these chemicals,but useful. I should research these topics a little bit more. Thanks. BF
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Old 05-31-2014, 04:02 AM #35
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Originally Posted by mrsD View Post
I think he should try the drug free nasal gel.... It really works, and won't interfere with his other medications. This is a new way to deal with pollen allergies.


It is so simple...you can do it even with Aquaphor ointment if you have some around (use a very very little bit around the opening to the nose, but not INSIDE the nose.
Thank you mrsD. I have allergies year round. You have given me something to consider,and thank you.

You,and Waves have allot of understanding of these allergies,and allergy medications.

I thank you all very much. BF
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Old 05-31-2014, 11:25 AM #36
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Quote:
Originally Posted by Brokenfriend View Post
I've read through some of the reports here,and I think that I might try Zyrtec for allergy rhinitis,and asthma. I don't have asthma,but I have a drip that probably sounds like asthma. BF
Yes, Zyrtec works well for a lot of people. It has very low interaction potential ... it's a very safe drug. Do try that. If it works, it will be marvelous.

The nasal applications are a good solution for sneezing and they help with the eyes. If the cough is a direct consequence of post-nasal drip, it might also help, by reducing the drip. If, however, your cough is due to bronchial hypersensitivity, a nasal spray won't touch it.

Quote:
Originally Posted by Brokenfriend View Post
Hey Waves. Thank you. I just turned on a lamp to see what they call this Durahist D Caplet Pro. I took it twice daily.

The generic says it's (P-EPHED HCL/Dexchlorphen/scop)
Steve,

Don't you also take Seroquel? Did your prescribing psychiatrist know you were taking this?

Besides dexchlorpheniramine and pseudoephedrine, that combination contains a scopolamine derivative. I'd be concerned about that in combination with most antipsychotics, but I don't know for sure what the implications would be.

From what I've been able to find on dosing information for that labeling, it looks like your Durahist-D might have just over half of the typical dexchlorpheniramine dosage. However, the methscopolamine would pick up the slack, by drying you out more.

That means the reaction you saw with the full regular dose of chlorpheniramine could have been due to an interaction at the full dosage. If you still have the chlorpheniramine in the house, you could try a halving the dose. I don't have a lot of confidence in that working, but it might be worth a try.

The "advantage" (for some of us) of the older antihistamines, including chlorpheniramine and dexchlorpheniramine, is that most have an intrinsic drying effect. The newer ones (Zyrtec, Claritin, etc) do not have that.

Anyway, do try the Zyrtec and go from there. Try it for a few days if you don't see an immediate result. Sometimes it takes a bit to get a reaction under control.

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Old 05-31-2014, 08:07 PM #37
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Hi Waves. I told my NP that I'm taking the allergy meds. I'm pretty sure that I mentioned that I was on the Durahist when I started taking it again. I probably told her when they phased it out. A year,or so went by,and I realized that I needed allergy medication again. I started taking the other allergy medication group that I mentioned. I don't think that she liked the combination,because I'm still on Seroquel. My pharmacist who knows I'm on these medications recommended those allergy medications. So I'm hearing recommendations from one,but not the other.

I know how much I suffer from allergies especially late at night. I do have a hypersensitivity below my throat when mucus drips,and I cough,and cough,and cough. I won't describe the rest of this because it sounds sort of gross. Saltine crackers help. I've been eating them for many years when I have allergy attacks. The salt helps. The saltine cracker is a very helpful aid for my allergies. The kind of crackers that I eat are the Premium crackers with sea salt. BF
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Old 05-31-2014, 08:11 PM #38
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I tried the Nasacort allergy 24 HR,but it doesn't work for me. I still see the commercials for this medication,and the commercial sounds good,but it doesn't work for me. It's very aggravating seeing this commercial now. BF
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Old 05-31-2014, 09:14 PM #39
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Steve, I don't know if you have ever tried homeopathic remedies before or if you believe in them.
I heard someone say that the allergies (or something like that ) one helps them.
I think it comes in drops that you could drink in tea.
Might be worth looking into.
Let me know if you try it.
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Old 05-31-2014, 09:36 PM #40
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Quote:
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I tried the Nasacort allergy 24 HR,but it doesn't work for me. I still see the commercials for this medication,and the commercial sounds good,but it doesn't work for me. It's very aggravating seeing this commercial now. BF
Steve,

That's a steroid... kinda surprising it didn't help, but sometimes, even with the prescription ones, the docs start you out at a higher dosage until sx are controlled. You probably can't mess with doses on an OTC one though.

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