| FAQ/Help |
| Calendar |
| Search |
| Today's Posts |
04-15-2013, 07:24 PM
|
#121 | ||
|
|||
|
Member
|
Quote:
"no, science can't answer this." --again is my reply. Im sorry----- I know this thought is obsessive and for that reason i tried to dig deep to find answer---- but there is no science i can find currently to answer this ? --I wont be online anymore tonight--- If i can locate any info on it I will def post it for you. |
||
|
|
04-15-2013, 07:34 PM
|
#122 | ||
|
|||
|
Junior Member
|
What I meant by when I said "extremely little depressed" is "hardly depressed at all." So putting that into perspective back into my question in my previous post, do you still say that science can't answer this and that we can't even guess what the answer is at this point?
|
||
|
|
|
04-15-2013, 07:39 PM
|
#123 | ||
|
|||
|
Member
|
Quote:
If you want my guess yes I think loss of pleasure would increase when level are high --meaning one would feel less pleasure ---but i think once the levels and stress decrease symptoms would improve drastically --just like they do with cushing disease improved once cortisol level are controlled . Im working on a project so I won't be back on tonight-- but should be here in the am --I hope this helped a little bit |
||
|
|
|
04-16-2013, 12:54 AM
|
#124 | ||
|
|||
|
Junior Member
|
Now what if the brain regions fail during chronic depression--brain regions that are responsible for making you depressed, controlling depressive thoughts, and attempt to gain back pleasure while the glucocorticoids are still overworking the neurons? Would you say that that the loss of pleasure activity only due to the glucocorticoids overworking the neurons is greater or less than the combined activity gained by these brain regions (combined activity that, this time, some of it being lost due to the failure of these brain regions, resulting in little gained activity)? Therefore, would you say that there are moments (a second or more or less or even longer) where this combined little gain of activity of those brain regions is greater or less than the loss of pleasure activity just due to the glucocorticoids overworking the neurons during chronic depression? Or, again, science can't answer this and we can't even begin to guess what the answer is?
|
||
|
|
|
04-16-2013, 08:55 AM
|
#125 | ||
|
|||
|
Member
|
The way this is worded added some confusion for me---- but I will tell you strictly my thoughts--not science--just based on my reading . If your asking me if a chronic depression person like yourself is on anti-dep meds and starts to feel better with depression symptoms. But that person cortisol levels are still high will there still be a greater loss of pleasure activity due to the stress hormones being high --my educated guess is YES. Because it shows that way mentally and physcially with cushing disease.
|
||
|
|
|
04-16-2013, 06:28 PM
|
#126 | ||
|
|||
|
Junior Member
|
3 more questions (again, please answer each one):
1.) For a person who has chronic depression, can cortisol levels still be high even during moments this person feels alright, still overworking and killing the neurons and still causing a loss of pleasure even if this person doesn't have cushing disease? 2.) In regards to my question in my previous post, your saying that the loss of pleasure activity due to the glucocorticoids overworking the neurons can be greater than the little amount of combined activity that is gained by those failing brain regions during chronic depression? (again, what I mean by combined gained activity is that brain regions like the amygdala and hypothalamus become active during depression). 3.) What if for someone who has chronic depression, that those brain regions aren't fully failing (they are only mildly failing. Therefore, not as much activity that is gained by those brain regions is lost). Do you still say that the loss of pleasure activity due to the glucocorticoids overworking the neurons can still be greater than the combined activity gained by those mildly failing brain regions? Last edited by MattMVS7; 04-16-2013 at 06:45 PM. |
||
|
|
|
04-16-2013, 06:50 PM
|
#127 | ||
|
|||
|
Member
|
Quote:
|
||
|
|
|
04-17-2013, 11:01 AM
|
#129 | ||
|
|||
|
Member
|
Quote:
This is what I know--- that there had been clinical test done with people without depression and chronic depression. All i know ppl with no dep showed cortisol in the bloodstream peeked in the am --then decreased as the day went into the evening. In 50% of chronic dep ppl--- it peaked in the am and did not level off as the day went on. Studies suggest ppl with chronic dep in someway who had higher cortisol levels may induce more depression ---lack of sleep eating more,trouble staying focused...etc. because in someway it affects the serotonergic neurotransmission. That 1000mg of Vit C 3x a day has been proven to reduce cortisol |
||
|
|
|
04-17-2013, 11:27 AM
|
#130 | ||
|
|||
|
Junior Member
|
Now when you say "3 ?" do you mean just the 3rd question, or all 3 questions (the last two asking if there are moments like a second or more or less or even longer where the loss of pleasure activity due to the glucocorticoids overworking the neurons can be greater than the combined activity gained by the fully failing and the mildly failing brain regions during chronic depression)?
Again, you can't answer or even guess at this question in parenthesis as well as those 3 questions? Again, just a simple reply "yes, I can answer and guess at that question in parenthesis as well as those 3 questions," or "no, I can't answer or even guess at that question in parenthesis as well as those 3 questions." |
||
|
|
| Closed Thread |
|
|
Linear Mode
