If ECT has not worked so far after 11 treatments, it is likely it is not going to work. I did not get better after 7 and quit because I just did not want more damage. I had already started to notice problems after number 6.

I saw my PCP today, and he thought Aricpet might be worth a try. I am sort of scared to try it. What if I try it and then quit. Will my memory get worse after I quit? Also, he said research shows now that extra B6 can cause permanent brain damage for some people. So I quit the b6 but still take the B12.

I would challenge that doctor on that statement! Make him prove it and doses need to cause it.

One cannot make serotonin without B6. The P5P version is better since some people cannot take pyridoxine B6 and convert it to the active form.

Here is a paper showing B6 is protective:
http://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum

I have a thread here discussing the potential toxicities of very high dose B6:
http://neurotalk.psychcentral.com/thread30724.html

The actual number of proven B6 toxicities is very very small..over many many years, and go back to when 500mg a day was used for PMS. (no longer recommended).