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General Health Conditions & Rare Disorders Discussions about general health conditions and undiagnosed conditions, including any disorders that may not be separately listed below. |
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06-22-2012, 09:26 PM | #1 | ||
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Junior Member
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My husband has been suffering for over a year now with an as-yet undiagnosed illness that include symptoms of peripheral neuropathy. There is so much first-hand experience on this site, I hope maybe some suggestions could come my way.
Here's a summary of symptoms and events that may or may not connect, but worth mentioning.
History of: diverticulitis, asthma, allergies Only unusual family history: Father has Myasthenia Gravis Radiology: MRI of brain & spinal cord, CT of abdomen both normal EMG and NCV: Normal Lab tests: Only blood work abnormal is Sed Rate (>100 mm/hr) and C Reactive Protein (>12). Muscle biopsy: Totally normal His 'diagnosis' right now is fibromyalgia, but we and the doctor both know that's not all this is. He is on a pharmacy of meds: Lyrica, Cymbalta, Seroquel, Tramadol, Hydrocodone as needed, and prednisone. The meds help, but don't eliminate, his pain. Prednisone is the ONLY thing that improves the muscle weakness. However, having already been on it for 6 months and seeing another rheumatologist, he is being weaned off of it for further testing. The more the dose is decreased, the more weakness returns. He's also having headaches every day, which are progressing to starting earlier and earlier each day. The new rheumo mentioned Gullian-Barre or another viral syndrome, but he's had no paralysis. Any thoughts would be appreciated. If the new rheumo can't diagnose him, our next referral will probably be several states away to a large clinic. |
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06-23-2012, 06:06 AM | #2 | |||
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Wisest Elder Ever
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Welcome to NeuroTalk:
I wonder in reading this history if your husband was given antibiotics in the fluoroquinolone family, or Flagyl? (there are others also less commonly used like Zyvox and Tindamax). Fluoroquinolones can cause tendon damage and ruptures. The ruptures may occur up to a year or more after use of the drugs. This family of drugs are also neurotoxic and can cause peripheral nerve damage and in the elderly can affect the CNS as well. This is thought to be permanent, but Dr. Jay Cohen, MD thinks some supplements may work for it. More information and links here: http://neurotalk.psychcentral.com/post661103-2.html There are suggestions that use of steroids and/or NSAIDs with fluroquinolones may make the reactions worse. The mechanism of this damage is not understood clearly yet.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei ************************************ . Weezie looking at petunias 8.25.2017 **************************** These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.
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"Thanks for this!" says: | ginnie (06-23-2012) |
06-23-2012, 08:53 AM | #3 | ||
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Junior Member
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Quote:
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"Thanks for this!" says: | mrsD (06-23-2012) |
06-23-2012, 08:55 AM | #4 | ||
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Junior Member
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Quote:
A side note... this information has me worried for myself as well, since in early May I took a course of Levaquin AND Flagyl for C. difficle colitis! |
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06-23-2012, 09:49 AM | #5 | ||
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Is he on asthma meds such as Advair? If so, how long? I have many of the symptoms you describe and they all seem to be dose related with the meds. I think my reflexes and speech have always been normal however.
judi |
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06-23-2012, 12:07 PM | #6 | |||
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Wisest Elder Ever
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Some people are more prone to damage for some reason.
There is a book written about this by Stephen Fried called Bitter Pills. His wife developed a permanent seizure disorder from ONE dose of Floxin. Floxin is not used much anymore orally. But Levaquin is a chemical derivative of it. http://www.stephenfried.com/bitter-p...pillsbook.html This is an interesting book, I have a copy of it myself. Doctor Cohen suggests magnesium for fluoroquinolone side effects. And with your hubby's high C-reactive protein, you might try high dose Vit C. There are studies showing Vit C will lower C-reactive protein. Also in patients with potential RSD (a form of neuropathy) high dose Vit C works as well. I'd use Ester C form (easy to tolerate) and at least 1000mg a day. Discuss this with his doctor to see if it would interfere with his other meds. This is a PubMed paper on C-reactive protein and Vit C: http://www.ncbi.nlm.nih.gov/pubmed/18952164 I hope he is not on a statin drug at this time...you didn't mention any. Statins are very hard on the nervous system and cause neuropathy in some people.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei ************************************ . Weezie looking at petunias 8.25.2017 **************************** These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.
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06-23-2012, 12:41 PM | #7 | ||
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He was only on Affair for about a week spring 2011. He did have an unusually bad spring that year as far as asthma.
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07-02-2012, 10:48 PM | #8 | ||
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silly question.. but what was his occupation. was he dealing with chemicals.. or possible plant life.. I know as a past landscaper. that drugs and contact with certain plants or continued exposure to sun can cause adverse reactions to the medicines he may have been taking... even construction workers deal with chemicals through treated wood, ,metals, insulation, paints etc.. I think its all worth looking into... good luck, my prayers be with you
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07-03-2012, 07:20 AM | #9 | ||
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Quote:
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07-03-2012, 08:42 AM | #10 | |||
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Senior Member (**Dr Smith is named after a character from Lost in Space, not a medical doctor)
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Offices aren't any safer than other environments when you think about it/dig in a little... Google: chemicals found in office air Doc
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Dr. Zachary Smith Oh, the pain... THE PAIN... Dr. Smith is NOT a medical doctor. He was a character from LOST IN SPACE. All opinions expressed are my own. For medical advice/opinion, consult your doctor. |
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