Is it possible for pressure to rise and fall over the day in a pattern that repeats each day (i.e. a circadian rhythm)?

I ask because of such a pattern in my own case which I have assumed to be Parkinson's. Diagnosed in 2000 and taking Requip and Sinemet.

One set of symptoms that have been an increasing problem for several years is finding myself stuck to the floor with a sudden and overwhelming need to pee. And it starts each evening at about 11:00. Also, cognition problems come at the same time.

Additional meds have minimal impact but going to bed a couple of hours brings noticeable improvement. By morning symptoms have reverted to simple stumbling and respond to meds.

How common is NPH as secondary to Parkinson's, too? Both could be at work.

Any clues?

It's certainly possible that you have a "pressure rhythm." Time, changes in air pressure, changes in wind direction, and other things can affect hydro, especially if it isn't treated. As far as having NPH in conjunction with, or seconary to, Parkinson's, I don't have an answer for you on that, but it's worth asking the right neurosurgeon. (NOTE: A neurologist will not have answers for you!!) Consider contacting the Hydrocephalus Assn at www.hydroassoc.org or info@hydroassoc.org and telling them what you told us. Be sure to tell them where you are so they can help you find a nsg close to you.

Good luck!

LIZARD

The more I have been reading the more I suspect a role for pressure fluctuations in PD, particularly the advanced stages.