My aunt and I both have RSD. She takes Cymbalta and has for several years now, and says if it weren't for her Cymbalta, she would have long ago lost it. I tried Cymbalta and it made me so sleepy, day after day, that I never could get to what my doctor termed a "medicinal dose" for my condition. I agree with the poster who said it really is a person by person thing....it's chemistry and we are chemistry, and at the end of the day, it just won't be the same for everyone.
I see the comments of jason0624 and they make Cymbalta seem very scary....and I tried a medication once (not Cymbalta) that did that to me....while others took it with no issues whatsoever.....and like I said, my aunt has been on it for years with no issues....