have been whining about fatigue lately, and the MD tried me on amantadine with out good results. Today he gave me an RX for Provigal.

Anyone else on this? What is your experience? Tips? Tricks? suggestions? I hate taking new stuff, but I cant get out of my own way. I need a boost.

I have had 2 boxes of provigil samples sitting in a closet for over a year. I have been afraid to try it. I REALLY hate trying new stuff. Hope it goes well.

Me too! I really really hate taking stuff.

Kim has been on Provigil for years, it's a real HUGE help for her.

She started out on 100 and was moved up to 200 a few months later, this was maybe about 9 years ago. She takes it in the morning and it gives her more "day". There are no down sides to this, unless you accidentally take one before bed

This also makes me think of something we recently learned about caffine. It turns out that cryptic CPn is a possible explanation of caffine crash or induced "MS" symptoms. I'm a caffine user, I need caffine. Some MS'ers have a unique caffine profile wherein you get a temporary burst, but then crash hard. (not the caffine addict profile) Kim was like that and it turned out to be CPn related. Just sharing.

Ken

I like Provigil. I only take it occasionally, though. I'm glad I had my rx filled (while I had insurance) all those times when I really didn't need to. that stuff is close to $900 for a 30 day supply!

it's not bad. it doesn't make you nervous or anything, at least me anyway.
i've tried it but it wore off by the afternoon and that's when i'm most tired.

i was told not to take it past 1 or 2 o'clock because i wouldn't be able to sleep at nite. i honestly could drink a cup of coffee and have the same effect. but, it was helpful.

Provigil
I have been taking Provigil as needed for over 10 years. I have never paid over $100 US dollars for this drug. Even if I don't need it, I still get it refilled and store it in my closet. It has a long shelf life. I'm using some now from 2006.

I have used Provigil, I didn't like it.

In my case: it made me very shaky, a side effect I cannot tolerate and in most cases I would be asleep 30 minutes after taking it.

To be fair, ANY stimulant has the opposite effect on me - they make me tired I can even drink coffee and go to sleep

You won't know if Provigil will help you unless you give it a try.

I took it for a while, and my neuro keeps renewing the Rx in case I need/want to take it again.

It did make me a bit jittery, hiked up my heartbeat, and gave me nightmares if I didn't really fine tune when I took it.

I'm pretty sensitive to caffeine also. Ask my husband--if I drink a half glass of diet coke mid-afternoon, I'll either be hollering in my sleep, or still talking four hours after he falls asleep. Or both.

If I need to be bright-eyed and bushy-tailed (as if) I'll have a diet vanilla Coke ahead of time. For me, it's about equal to Provigil in efficacy.

I'm taking Provigil now. I tried in in the past but it made my blood pressure go up for some reason. This time that isn't happening, go figure. It seems to keep me awake and I can get more done. I'm trying to find another job and hoping this will allow me to keep working. I get killer fatigue and it's hard to get myself moving and get things done.

The real test will be if I find a full time job and see if I can handle it. At my last job I worked four, ten hour days so I rested midway through (had Wed. off).