My lesions are also atypical. Mine are mostly subcortical, too. I do have more than one, though. I don't have an official count, the neuro just says "a bunch of them". My neuro says it is atypical MS, or CNS Demyelinating Disease, but won't go with an official dx or prescribe a DMD. He lets me have IVSM when I am not doing well and gets me the sx drugs I need.

One neuro suggested to me that this is PPMS because my lesions are smaller and in atypical places. He said that was more common in PPMS. It sounds like you have a very good neuro.

Hi Holly thank you. I think I have a good neuro too. He does think it is PPMS. He is asking for all of my previous films to compare.

He did not dx me so he is trying to get up to speed on my situation. I know this MRI report does show progress and I have not even heard from the doctor yet.

My last MRI showed nothing in the periventricular area but this one does although the areas are not exactly MS shaped.

I have been on DMD's for about 18 months now. I have such pressure behind my eyes. When I started the
DMD that pressure went away. I was off DMD's for 2 months to change to another and that horrible eye pressure came back. So the DMD's are doing something for me.

Thank you for posting. Some of us are odd balls!