The Bioperine does work. However, people using OTHER drugs may be at risk with it. There are just not very many studies of alot of drugs to show how it alters their absorption too.

I'll give you an example:
The work concerning grapefruit juice... took over a decade to evolve and started with one drug...Calan and expanded to many many drugs, if not MOST drugs out there. Grapefruit juice inhibits Cytochrome P450 which is in the lining of the GI tract. (as well as the liver). It was not understood that this barrier was there, and our drug studies developed doses for drugs based on how people absorbed them. Once you CHANGE that and enhance absorption, then people could get OVERDOSED.

This is what Bioperine does...it also enhances absorption. I did alot of searching a while ago looking for data, and it just does not exist for most drugs. I believe Dilantin was one affected.
This is an old paper, but not much has been done since 1985.

So now we have piperine (Bioperine) added to supplements to enhance their absorption. I just think it has to be used cautiously and by people who are NOT taking other drugs.
More here:
http://www.raysahelian.com/piperine.html

Posting on a board like this, one never knows who is reading what. So I cannot give a blanket recommendation for using Bioperine enhanced Curcumin.
I use the epic4health Curcugel 500 myself.
I also add curry spices to my soups, so I eat it too.