marinol isnt available in my state, unless you are in hospice care. The gov signed a bill preventing its use here. Way to go John!

I tend to react like Barb. I am overly sensitive to things. My biggest fear is that I will be a zombie, or nauseous to the point of being paralzyed anyway.

I have taken buspar, and like xanax better. I am not an addictive type person, so I can take xanax for a year, and simply put it down. Most of my family is the opposite. They smell an addictive drug, and are hooked for life!

I have heard effexor, and a couple of others made folks sit on their couches like a zombie till they got adjusted. I didnt see it personally, but I dont want that! Take an anxious girl, and tell her you want to give her pills that makes others not feel well...what do you get? a more anxious girl.

I am thinking IF i allow any of them, I may try celexa. i hear its mild, and prevents anxiety from forming in the first place.

I hate this stupid disease! I have to take one drug to cover another! I swear, its the copaxone that is keeping my anxiety level flying.

(((Dej))) It is a trial and error type of thing. I take an AD as part of my pain management regime. They started me on Cymbalta, which worked awesome for pain, but NOT my emotions. I am a passive, calm (unless in pain - then I get anxious) type person. By the 3rd day I was having aggressive type thoughts. Scared the carp out of me. No more Cymbalta for me.

Next up was Paxil which worked great for a little while. Then my affect went flat.

I now take 5mg - 10mg (alternating days) of Celexa (generic). It works ok, not quite as well as Paxil for keeping me calm during painful times.

Also, there are a few groups of AD's and each work on different synapses and neurotransmitters within the brain. Cymbalta is a SNRI while Celexa and Paxil are SSRI's, which could explain why Cymbalta did not work for me. This is a link to a fairly good article on different ADs and how they work. If you want an more in depth one let me know.

http://users.rcn.com/jkimball.ma.ult...ntidepressants

Hang in there, Dej and know that we are here to help you through this.

Oooo...I forgot about the aggressive thing with Cymbalta! It did the same thing to me. Made me real pissy (can you say "pissy" here? Ooops. Said it twice). Ask anyone who knows me, this bear is too lazy to be angered easily.