http://www.pdrhealth.com/drug_info/n...nic_0183.shtml

http://www.patient.co.uk/showdoc/30003248/

Description of Nicotinamide

Hey! I'm ready to order large quantities of this stuff, anybody else? The only thing is, I don't know how much to take. I don't want to take too much and distroy my liver, but I don't want to take so little that it doesn't do much good.

Anybody taking this form of B3 (Nicotinamide), and if so how much? I hate to jump the gun, but it is an available supplement, so I might as well try it, 'cause I'm getting old waiting for a cure.

Wadda ya think?

Sounds promising but so did many other studies using mice. Somehow they don't seem to translate well to humans??? Maybe we should try to grow tails!!!

Keeping fingers crossed anyway!!

Yep, you're probably right, Judy. We have the healthiest
un-healthy Mice in the world.

On the other hand, it's a vitamin and it's cheap.

I tried some niacin yesterday (I forgot about the flush). I felt totally sick from it and I had the worst stomach cramps, just these waves of very acute pain that doubled me over until it passed. My skin was red as a tomato all over, from head to toe. Not sure why I got so sick or if I should try to find one that doesn't flush the person.

I asked over at the new Vitamin forum here if anyone has any info on B3 that they could share about doses, side fx, etc. Hopefully one of the local gurus there might be able to help us to understand more fully effects of taking B3.

I thought the B vitamins weren't very risky. Then again I never expected to be sick yesterday either. I swear it felt like I was having contractions.

You don't want Niacin. Just get the "Nicotinamide" part of B3, it's the non flush part of Niacin. That's what I learned, anyway.

Here is some niacin/nicotinamide info for you.

Basically nicotinamide has less potential for causing the dreaded flushing(which for some is very uncomfortable)

However in very high doses nicotinamide shares toxicity warnings that
are attached to niacin also.
Here is a really good monograph from Linus Pauling Institute on both:
http://lpi.oregonstate.edu/infocente...cin/index.html

Long term niacin/nicotinamide should be monitored every 3 to 6 months with a liver test at the doctor's.

I skimmed the research and it is unclear to me how much you would need.
The toxicity listed at Linus Pauling Institute would be a guideline for you.

While it is true that the B vitamins are water soluble, and hence to not build up in the body, Niacin has other effects at high dosage.

This article also discusses NAD which is in the research articles posted here.

You can use NAD as a supplement... The NOW company makes it:
http://www.nowfoods.com/?cat_id=2822
The link above explains it.

I am sorry, I cannot advise you about doses to use.
There is a warning in one of the articles that very high doses would be needed for humans...and that would necessitate physician supervision. (we are talking in the gram range here). 500mg/day of nicotinamide is not essentially harmful, but it may be too low for your purposes here.

It is interesting none the less. I found an article in Science News, on MS, this week, using a new drug (actually an old drug recycled for this purpose).
I'll post that later today in a new thread.