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I must say that I do think that the nerve death is related to the increased loss in volume of the brain because the area of the brain that shows up in a MRI as "enhancing" is REAL inflammation (dying tissue) after which comes the formation of scar tissue which occupies a smaller volume. Given the number of "enhancing lesions" I had I am very lucky that my brain does not look like a "raisin" in size and shape. I am very glad I have at least a prune size brain. jackD
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