Laura,

I was on Tysabri for about 2 years but stopped (because of the cost associated with the infusion and the additional lab work which totaled six figures over that time, even though I had insurance and Biogen cut the Tysabri cost down to 20% for me).

My MS has been running its natural course of increased fatigue, mobility loss, and other simple losses. BUT, those functional decreases may have nothing at all to do with being off of Tysabri. It may (as I suspect) just be the natural course of MS.

I wish that I had more concrete data for you.

I would ask your physisican about other DMD's or experimental surgical treatments (angioplasty) that that could help.

I wish you the best.

-Vic