I've been using low dose dextrometorphan as an alternative to LDN for Parkinson's disease for more than six years of the ten years I have been diagnosed, with what I feel is good success.

I buy over-the-counter pediatric preparations (PediaCare, Triaminic, etc) that contain 7.5 mg of dextromethorphan hydrobromide per 5 ml (1 tsp). It is important that the cough syrup NOT contain any other active ingredient such as guafinesin, polystyril, antihistamines. I take 1/2 tsp every night at bedtime, which should contain 3.75 mg of the drug.

Dextromethorphan (DM) and naltrexone are both morphinans which have been shown to be powerful anti-inflammatory drugs, demonstrated by the research by Dr. J.S. Hong to be especially effective in neural tissues of the CNS. Because of the long history of safety of DM, I feel very comfortable in using this inexpensive, non-prescription drug as a neuroprotective agent.

Robert Smith