Welcome Mike to NeuroTalk.

Choosing a DMD is like a crap shoot, if one doesn't work, try another one, except "G"...stay away from that one for awhile. If the others don't help, then you could try Tysabri, but only after you test for the JCVirus, to make sure you are not in danger of getting PML.

In the Meantime try som LDN(lowdosenaltrexone..look it up..)...shouldn't hurt, may help...

Good luck in whatever you choose..

I've tried Gilenya and Rebif. If I had to choose I would choose Gilenya, because I hate needles. I want to try LDN but I have to find doc that will prescribe it. Right now I don't use anything. Gilenya was too expensive even with ins. and co-pay assistance for me.

You have too see which fits into your lifestyle and what your comfortable with. My previous neuro said that Tysbari was if the other DMD's didn't work. I switched to an MS specialist who is non responsive. Now I have to find another neuro. Find a good neuro that can help you through this and help you find treatment that fits you.