Yes Erika, thank you for your reply. Your concerns were very well stated. I think I will be able to account for all of the things you mentioned. I am hoping to show that the disease process is a pathway that originates with PEDD. There are numerous ways this pathway can be interrupted, many of which you mentioned.

I liked your analogy of the bean sprout. This is much like the PEDD Pathway. I do think the cause and effect with PEDD is well defined. Much like an ulcer resulting from H pylori or gout resulting from high levels of uric acid.

I am going to list symptoms and findings in MS, and then show how they would be a direct result of missing pancreatic enzymes. I want to include every symptom and finding, so if I miss any please let me know. We will even include overlapping diseases.

White matter lesions
Optic neuritis and other vision complications
Ataxia, vertigo and other coordination and balance problems
Dysregulated iron
Low B12
Low vitamin D
Bowel and bladder problems
Restless leg syndrome
Muscle atrophy
Lack of glutathione
Low human growth hormone
Low tryptophan
Lack of essential amino acids, such as phenylalanine, leucine, valine, etc.
Depression
Dementia
Cognitive dysfunction
Fatigue
Sleeping difficulties
L'Hermitte's
Paraesthesia
Trigeminal neuralgia
Hormone imbalances, such as low testosterone
Increased risk of developing hypothyroidism
Increased risk of diabetes
Increased risk of Sjogrens
Heat Intolerance
Increase risk of developing certain types of cancer, such as lymphoma
Migraines
Vascular complications
Elevated tumor necrosis factor
Swallowing problems
Epileptic seizures
Autonomic nervous system dysfunction
Spinal cord degeneration
Mitochrondrial dysfunction
Lack of noradrenaline
Reason why gout and MS are almost mutually exclusive
Chronic itching

Please feel free to add to this list.