I have had now 5 IPIR's with copaxone. Just had my last one saturday. Injection was fine, but 50 seconds later, my hands turned beat red and felt like they were swollen and on fire, my face and ears did the same thing, and my throat felt like it was closing and such an intense stabbing sharp pain in my lower back. My lower leg also felt like it was on fire. Called SS and they said I had all the symptoms of IPIR and not to take any more shots until I talk to my doc. Well, thats enough for me. This was the most severe and it scared the daylights out of me, so, Im done. No more. Its now Monday, and Im finally feeling a bit better. Took along time for my body to get over that shot. My throat still feels a bit closed off, but not as bad. I dont really care what my neuro has to say about it, Im done. I'll ask for LDN, but none of the dmd's. Sometimes I wonder if this is all worth it. MS is going to do what its going to do no matter what I do. All these chemicals I put into my body, could they be causing more harm than good???

I don't blame you. Sometimes the stuff that's supposed to help us ends up hurting us more.

Same thing here. I did have a good 2 years though. My last 4 shots I spaced out 4 weeks inbetween. Guess I'm a slow learner. I had to lay on the kitchen floor(because it's cooler there) until I cooled off. Did LDN next and now Tysabri for 4 years. At least I'm stable now.

that sounds just awful. i don't blame you for quitting it.

I never had one of those with Copaxone, but the very first one would have set me running for the hills.

I'm glad you're off of it. Good luck with LDN. I hope it helps you to feel better,

I'm scared to try a new drug. I have a drug which is off-label to increase Dopamine, used by Parkinson's patients. To stop the spasmodic jerking which is in my left leg and hip and which sometimes keeps me awake. It's breaking through into daytime now. I'm sitting here jerking. Feel hopeless but I already am doped out by taking both demerol yesterday for pain (rare for me to do that) and Zyrtec antihistimine for itch. I can hardly drive and I have to drive. I can't take one more thing to make me stupid. So I'm where you are, KittyLady, just fed up with drugs.