I took it years ago when I had a bad case of food poisoning. It helped with the nausea but I didn't like the way it made me feel. I have not taken it since. In fact, I haven't taken any antinausea meds since that time other than when they gave me morphine in the hospital when I had a bad exacerbation last year. But, they gave me Zofran. I liked Zofran much better and was able to tolerate it well. Zofran is expensive though, even with insurance.

Yes, Phenergan is not the best anti-nausea drug.

But supply problems have plagued the other two drugs previously used. Compazine and Tigan are much stronger.

Prochlorperazine (compazine) has stronger phenothiazine side effects too. It is typically only used for a day or two for GI viruses/food poisoning. Daily use is discouraged today.
http://en.wikipedia.org/wiki/Prochlorperazine

https://en.wikipedia.org/wiki/Trimethobenzamide

Zofran remains highly expensive. It was originally developed for chemo nausea, but they use it now for other types including migraine. Even the generic costs alot.

There is an OTC product called Emetrol.
http://emetrol.com/

It works like Coca Cola syrup directly on the stomach receptors, to block the signals going to the brain. It is mild but effective for some people. Wears off fairly quickly, but much safer than many of the RX drugs.

Phenergan is better tolerated but also has weaker antinausea actions. It was at one time very popular in RX cough syrups.
There is a Phenergan cream in Canada OTC for itching. Or was last time I was there.