Hi All,
I'm new here and I puzzled as to what' happening to my body, as my neurologist think my case is " interesting adn something is wrong". I have had negative antibody testing for Myasthenis gravis but has textbook symptoms includes Ptosis worsening with extreme fatigue and exertion, drunk like feeling, generalized muscle weakness and only sleep and rest help. Long history of shortness of breath with 2 abnormal pulmonary function test and one normal. Cause unknown. My condition does not appear to be going away or getting better that my neurologist is starting me on Mestinon after Optos arteriogram of the eyes to rule out Von hipple Lindau due to right sided weakness from face to feet which has impaired my gait significantly especially with exertion. I'm going to PT without a significant change in how I walk .

Also with history of proximal Myopathy with cause unknown with extensive lab test but abnormal EMG and physical exam ( hypereflexes in leg and balance issues).The gait is more worsen with exertion and fatigue. I to use a cane to walk and I'm 43 years old. Do any of you with MG have these symptoms. I have history of enlarged optic disc. I've also been diagnosed with small fiber neuropathy due to abnormal QSART. Can one have both MG and MS and is the right sided weakness more likely with MS or MG. MRI without contrast ( allergic to contrast) reveal white matter changes. Thanks for taking the time to read and respond. Your advice is greatly appreciated.Thanks again

Hi Starflower 12. Welcome to the MS forum of neurotalk.

Yes, you can have both MS and MG. Unfortunately, if you have one auto-immmune disease your chance of having a second is higher than the general publics.'

I hope you get some help, answers and energy.
ANN