In my experience, docs don't like to be second-guessed so I'd say that your best bet is with a trustworthy doc. I try to remind everyone that for us, our neuro is a lifetime relationship and the right one is essential.

When you have a good relationship, you can freely say, "Hey, if you don't know, let's find someone who does!" (in so many, diplomatic, buttkissing words)

My neuro and I are exploring our next lines of defense and she recently asked me if I'd be more comfortable adding another doc to my team, a well-regarded specialist 3 hours away. Because we have a good doc-patient relationship, I was able to say, "let's see what you come up with and how confident you are with it and go from there," she was fine with it and we decided to meet again in Nov.

Where I'm going with all this blither is that I defer to her expertise and she reciprocates by including me in the process. It's a good relationship.