Hi, Friend2u, i think we can all understand where you are coming from, i followed the link that one of the others provided and i agree that it is the best description of fatigue that i have come across. Fatigue is such an innocuous term, it sounds like nothing much but of all the symptoms i have, this isthe toughest one to deal with. as for the anti fatigue medications, i hve asked 2 neuros and my Gp about them and have been told that they are not used here in australia (mainly because there is no proof they are effective- thats the comment from the medicos i aksed) but i know many of you guys use them and get some relief from them. All they have suggested to me is to see an OT to get advice about energy conserving strategies to use, i did this and it seems they can't suggest anything i am not already doing. Hope things get better for you