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Old 02-13-2009, 09:25 AM #11
Harry Z Harry Z is offline
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Join Date: Sep 2006
Location: London, Canada
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Harry Z Harry Z is offline
Member
 
Join Date: Sep 2006
Location: London, Canada
Posts: 241
15 yr Member
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Quote:
Originally Posted by lady_express_44 View Post
It's not the risk in disease progression that is reduced by 68%, Harry, it is the number of relapses that is reduced by 68%.

They really don't expect to see disease "activity" in the way of lesions popping up or getting bigger while people are on Tysabri. Some % of people are ALSO seeing a reduction in disability accumulation too, but having very little lesion activity is what they are measuring to determine "disease progression".

Cherie
Hi Cherie,

Got my numbers crossed.....the Affirm trial showed a 42% Reduction in the Risk of Disability Progression and Sustained 67% Reduction in Relapse Rate. That would mean that 58% of patients could have disability progression and 33% have relapses.

For some docs to say that it is extremely uncommon for MS patients to have disease progression or replapes while on Tysabri is really stretching it, don't you think! Just reading comments on other MS Forums from some patients on the drug seems to negate that kind of statement.

Take care.

Harry
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