Hi again,

Yes, I still hate this disease. Another day, still hate it.

I take provigil - 400mg a day. Don't know that it's doing squat for me. Sigh.

Has anyone tried DAYTRANA for fatigue? It is used for ADHD (like provigil is) - it is also used for treatment of narcolepsy. My psychiatrist mentioned it to me when I told him the provigil wasn't cutting it - and he suggested I mention it to my neuro (since other ADHD meds are often used for the fatigue).

I'm looking into it - as I had gastric bypass several years ago - and I don't always absorb all pills properly - and things that are supposed to be long or extended release don't really do their job rights. Daytrana is actually a skin patch - so it wouldn't need to be absorbed through the stomach.

I will ask my neurologist tomorrow when I see him....but I'm curious if anyone has heard of it or tried it, etc.

What other meds have people tried for fatigue besides provigil?

I know amantadine/Symmetrel is also used....

Any others? I heard someone once say prozac has been used...but I'm already on another antidepressant. LOL.


Anyhow...last Sunday I felt great - I went to brunch with friends....then I got into my car to drive home - and felt like a piece of dead wood - I couldn't move to even drive home. I had to sit in my car for over 25 minutes before I could muster up the energy to drive - and that was on the provigil! (And I ain't NEVUH speechless!)

~Keri

ps/we need to work with neurotalk to get some more funky icons on here!

Hello,

I took Amantadine several years ago, while it works for many, it done nothing for me.

I now take Provigil (400mgs daily). May I ask what dose of Provigil you are taking? I hadn't heard that Provigil is used for ADHD - but can understand where that may be possible. I've also heard that Prozac can be helpful with fatigue.

Provigil gives me no extra energy. In fact, I can take it and go right back to sleep. I really only know that it helps me when I don't take it. It does help me to "Function" - be able to put my thoughts together etc.

I've never heard of Daytrana. Having had the gastro bypass, it sounds as if the patch may work better for you since you have problems absorbing things when digesting them.

I know other meds for ADHD have helped many with fatigue (Ritalin, Adderal etc) so I suppose it's possible the Daytrana, being a med for ADHD, could help. My daughter has ADD (along with many other health issues) and now takes both Strattera and Concerta. She has taken Ritalin and Adderal in the past. Neither worked as well as the ones she is on now and the Adderal caused severe weight loss.

Sorry that I can't be more helpful - but I would suggest that you discuss it with your neuro.

Please let us know what your neuro says and how you're doing.

Hope you have a great weekend!

btw: Another day, and I understand - I still hate MS too!

Wow, Duva, definitely sounds like your daughter has been thru the gamut of meds....glad you/she found something that worked! And am glad to hear the provigil helps with putting your thoughts together. I'm not sure if it is helping with that. I'm just trying to function - in the most basic sense - who cares if I make "sense" lol.

Oopsie...I forgot to put the dosage of provigil....I'm also on 400mg of provigil. I can also take it and go right back to sleep. I also just re-read something - and provigil is and isn't for ADHD. It was made for narcolepsy....however, an official off-label use for it is for ADHD. I remember one of the first few days that I took it - and I was in Staples (an office supply store) - and was in the pen aisle - and I was totally tripping out b/c I couldn't focus on anything (not visually - though that was an issue, too) - but there was so much stimulation, I was bugging out) - and I totally thought - this is giving me ADHD!

I'm definitely going to ask my neuro about the daytrana. Sounds worth a try... (Of course, at this point, I'm so , , , , , , , , , , , , and , etc. that I will try probably anything, even if it means that I will grow a rat's tail!)

I'll let you know. Of course, I have hours to go.... My puppy woke me up in the middle of the night AGAIN. Yes, I was given a puppy for Xmas....she arrived a week before the diagnosis came - right before my flare-up hit it's worst. I can barely take care of myself, let alone a puppy and am at my wit's end (see icons above!!). I nearly fall over every time I have to pick up a wee-wee pad. Especially at 5am.

~Keri

Well, now I'm replying to myself. (Is talking to oneself a symptom?)

I saw my neuro - and we agreed that my symptoms are returning - this flare up isn't dying down...but anyhow - the point of this thread was regarding fatigue...

Doesn't seem that the provigil is doing anything... I mentioned the daytrana...he didn't know much about it - so he called the phamacist downstairs....and he is willing to give it a try and he gave me a prescription for it.

Is is a very new drug apparently (wasnt even in the doc's system - they are VERY computerized in his office) - and none of the pharmacies in my area even have it in stock yet - and I live in a major city. So, I will have it on Tuesday and will give it a try.

Actually - it's technically and "old" drug - but the patch form is new.

I also signed the paperwork for Tysabri...but that's a whole different thread.

Wondering still what else others do for fatigue (other than nap 24/7).

~Keri

Never heard of Daytrana - but I'm ready to call my neuro anytime I hear of a fatigue med.



I tried amantadine, nada (or make that nod - a) and provigil helped for a while then quit on me.

My neuro and I talked about combining them, but A makes my stomach hurt - the only part of my body that is, so far, okay. I didn't want to go there.

I was thinking of something that would just up the efficacy of the provigil, but things that do so also up the side effects - like headaches, cog fog.


Grapefruit juice can boost efficacy of statins like 17x - that's a bit much, if it affects provigil the same way.



But peppermint is only 2x. I may still try that for now, see what happens. I still have a few Pro's laying around.

If you try that other stuff, I'd like to know what you think of it.

Keri, I don't know when your last attack was, but I was under the impression it was very recent....and if that is the case, maybe you should allow your body to sleep when it needs to sleep. I am a big believer that your body heals itself while it is sleeping.

If I'm wrong...and it has been a long time since the last attack, the only two meds I'm aware of for sleepiness have been mentioned on this post.