Friday I went to see both my PCP and my neuro regarding possible depression and significant cog fog.

The decision was made to first stop the Topamax that I've been taking for migraines. Apparently, it has been known to cause cog fog in the first month or so for some people. Even though I've been taking it SIGNIFICANTLY longer than a month, I'm one of those people that usually get all of the weird symptoms. So.....

I'm weaning off the Topamax. Once I've been off for a week, I'll start Lexapro. It's an antidepressant with few side effects.

Once I've been on that for one month, I'll start on Aricept. If I get to the point that I still have the cog fog and the Aricept isn't doing the trick, I'll try Namenda (works by a different mechanism than Aricept).

Keep your fingers crossed for me :-)

Good luck.....I hope it works for you and gives you some improvement.

I've had serious cog fog the past couple of days. Everyday things just take me SO long to accomplish and I feel like I have to double check myself all the time.

That sounds like a great plan. Fingers crossed and please keep us posted. Jules

Thanks for posting this info, Victorya. My DD is on Topamax and the first month, she noted cog fog. But, she had her dose lowered and seems better now.

I empathize w/any one who suffers from migraines. Keep us posted on how the new meds are doing. Hope you see improvement...

I would be curious if you ever go on Namenda, how you feel. My doc put me on it once for pain management and my spasticity improved and I felt more fluid in movement.
Had to go off it when insurance decided it was not intended for MS. Boo

Good Luck and tell us how these work for you!