I'm on Rebif. Just celebrating year #3 on it. It's not so bad. You stay on it until you have a reason to come off of it (eg. a cure!, a new treatment, you get pregnant, you can't tolerate it, etc.) It's meant to slow down your progression. It will only do that while you take it.

I was petrified of shots in the beginning. I started with Avonex. That's the intramuscular one (really long needle). It was hideous. Then one day I had to do it myself. It was hard but very empowering. After two years, I switched to Rebif. Not too bad. It comes with an autoinjector so you don't have to give the shot manually if you don't want to. I did it with the autoinjector for the first year but then switched to doing it manually because I can inject slower and I think that it hurts less. If you work with firefighters, you'll be sure to have someone who can inject you. Many have been trained as paramedics. Giving a shot is easy, once the nurse teaches you, if you don't think you can do it yourself, you'll at least be able to talk some brave soul into doing it for you. You can do this!

You can also take them any time of day you want. I choose evening because I can sleep though most of the flu-like side effects, but daytime works too.