Welcome... from one Biffer Babe to another. I have been on Rebif for 2 years now and I am tolerating it very well. The side effects only lasted for about 6 months or so, and I injected at night before I went to bed so I slept through them. Now, I can inject any time of the day, no side effects, no red marks or welts.

I completely understand the fear and apprehension of giving yourself a shot. It is scary. I use the auto injector which helps because it gets it over with in seconds and I don't have to see the needle going in. However, I still jump a little when I do it and I sometimes have to psyche myself up to push the button.

But, it is working for me. I have not had any major flares in the last 2 years and my MRIs show no new lesions and the existing ones are less prominent. Woohoo!

Good luck with everything. You will get a lot of help, support and understanding here. Keep us posted on how it goes.