Have you talked to your neuro and let him know what is going on???

I still don't premedicate. I haven't had any adverse effects, but you can be sure if something like this kept happening, I would be talking to my neuro ASAP about it, and the premedication, having an antibody test, and trying to get to the bottom of it. I am still scheduled to see my neuro every three months, just to keep up on what is happening. We will move to a six month schedule after this coming appt, but he always said if ANYTHING is going on that concerns me, to CALL HIM!!!

I'd also ask them if they are mixing the med beforehand and refrigerating it? Some clinics do that. It can be stored, mixed, under refrigeration, for up to 8 hours. My place doesn't mix it until I get there and they have all the answers to their questions, so they don't waste the med if I don't answer the questions to their satisfaction. Having a cold infusion can lower body temp a few degrees.

I hope you get some answers and that it all works out for you! Please let us know how it's going!