Sally, I am confused. It happens alot. Does LDN boost your immune system. I have been told to avoid vitamins that do so. Doesn't copaxone suppress your immune system? And yet, you can take LDN with copaxone. Is the LDN organization recommending it for those with RR ms or just more progressive cases?

I am also wondering if anyone has found out anything more about whether or not LDN and immuran are incompatible.

My neuro has told me that LDN is just providing a placebo effect. Of course, he is the one that does not want to prescribe anti depressants or stimulants either.

Barb, LDN is not an I mmune system booster persay....It does raise your endorphin level which in turn, helps to correct your Immune system response as to, not attack your myelin.

Just as the Interferons say they are not IS suppressants(..they are, rather modulators, LDN is not an IS booster, rather, also a modulator.

Oh and LDN is recommended for all types of MS.

It's an opioid antagonist (a drug that neutralizes or counteracts the effects of another drug) I havent been able to find anything that says it boosts the immune system.

So, I guess for some reason, in the low dose, the receptor that the LDN works on, must have some problem...recepting...when the person has MS, and the LDN must somehow make it more...receptive...

I have no idea if I'm right about this, but maybe the MS makes our bodies either not produce enough of a chemical, or makes too much, or makes certain receptors in our bodies not work right...and the LDN either increases or decreases the chemical, or it makes the receptors of the chemical work better.. I dont know.... but something about the LDN helps some people with MS. Why it helps some people and not others, I dont know.

I'm going to ask my neuro about LDN next week when I see him...hopefully he wont refuse outright to give me LDN...and hopefully I'll be one of those people who can be helped by the LDN.

I believe this is the link to an interview with Dr Skip Lenz (Pharmacist), where he explains the immune modulatory effects of LDN:

Scroll down to:

Health Talk, August 22, 2007
On this exciting episode of Health Talk, Dr. Hoffman is joined by Dr. Skip Lenz. They discuss Low Dose Naltrexone (LDN), how it works and who should be taking it.

http://wor710.com/pages/48794.php

(I haven't time to listen to it right now, but if someone who does will let me know if this is the right link . . . thanks!)

Cherie

I have really never seen anything about LDN and alchohol. Is that a potential contradiction?

If you take LDN, can you have a drink now and then? Does it mess with the effectiveness of the LDN?

In the higher doses of Naltrexone it's used to help you with your addictions of alcohol and opiads, but at the LDN doseage levels, it doesn't work that way. Of course you cannot drink to excess but a drink a day for a non-acoholic, is not going to hurt.

Serious question...how would you define excess? I would say that a few times a year I make up for that drink I don't have every day!

I really have been curious about this.

Yes, it is the correct link. Just search for the date 8/22/2007

Great link, Cherie, I've heard it before. There is also an interview out there with Dr. Bahari. Both interesting.

Everyone keep in mind, though, that Skip Lenz is not a Doc and even though it's true, he knows a lot about LDN, it's effects and mechanisms, and probably the best at compounding it, it is Dr. Gluck of the LDN.org who is the expert, as a Protege of the founder of LDN for MS, Dr Bahari.

Good luck with your Neuros and PCPs to write your Scripts.