It could just be me.... but yes it did. (Anyone else weird like me??)

When I flew to Minnesota in February I wasn't able to put it in the fridge...and I wasn't doing well by the time we got back. But actually missing a dose was totally different. Now there were other factors (very little sleep, uncomfortable hospital furniture, a tad bit of STRESS) and it may not have been all the missed dose... but either way, I'm not risking it again.

Oh, and I don't forget because I set the alarm on my cell phone. It automatically goes off every night at 11:30pm to remind me if I haven't taken it by then.