For me it has turned the clock back on some (but certainly not all) of my symptoms. I am more ambulatory, and my manual dexterity is much improved. As for LDN’s ability to stop progression, I cannot say as yet. I have not been on it long enough to tell. I have, over the past decade, experienced a noticeable (and sometimes frightening) decline in function. I expect that over the next few years I’ll be able to report what trends become obvious to me. Until then I am hoping for the best, and staying prepared for the worst