of Bcomplex are you using? I ask because too much B6 can be harmful and give neuro symptoms.

B12 has long be linked with MS. (some people mistakenly diagnosed actually have B12 deficiency)

I would not go over 50mg of B6/day.

B12 is needed by the body to convert serotonin to melatonin (which is our sleep hormone).

Also, magnesium oxide is terribly unreliable. New studies have shown that from a 400mg tablet about 8mg is absorbed. (volunteers had blood levels drawn after taking various forms.)

I have a magnesium thread here that explains elemental doses and which forms work best.
http://neurotalk.psychcentral.com/thread1138.html

Magnesium oxide remains on the shelf fooling people however and doctors (who keep it in their therapeutic handbooks which are never updated).
from: http://ods.od.nih.gov/factsheets/magnesium.asp

Magnesium is valuable for everyone including MS patients because it helps with muscle functioning and reduces cramping and twitching. Estimates are that up to 70% of Americans are low in this mineral!

So be careful with B-complex. Watch your dosing!