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Old 09-29-2008, 08:02 PM #1
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Default Cytokines info playground

If you happen to be research minded and a little weird then this "CYTOKINES INFO PLAYGROUND" will satisfy all your cytokines info needs.

http://www.copewithcytokines.de/cope.cgi

http://www.copewithcytokines.de/cope.cgi?key=MMP%2d9

Check out this page on NGF -Nerve Growth Factor

http://www.copewithcytokines.de/cope.cgi?key=NGF

Note the fact good old reliable Vitamin D3 causes our brains to produce more NGF Nerve Growth Factor came as a real surprise to me. Vitamin D3 also lowers MMP-9s.

This "potent producer of NGF" is another reason to take a LOT of Vitamin D3.

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Old 09-29-2008, 08:04 PM #2
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Originally Posted by jackD View Post
If you happen to be research minded and a little weird
Cherie's my research minded girl. I'll take full credit for being the weird one.
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Old 10-04-2008, 10:45 PM #3
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If you happen to be research minded and a little weird then this "CYTOKINES INFO PLAYGROUND" will satisfy all your cytokines info needs.

http://www.copewithcytokines.de/cope.cgi

http://www.copewithcytokines.de/cope.cgi?key=MMP%2d9

Check out this page on NGF -Nerve Growth Factor

http://www.copewithcytokines.de/cope.cgi?key=NGF

Note the fact good old reliable Vitamin D3 causes our brains to produce more NGF Nerve Growth Factor came as a real surprise to me. Vitamin D3 also lowers MMP-9s.

This "potent producer of NGF" is another reason to take a LOT of Vitamin D3.

jackD
Here is a little tech info on what cytokines are and do.

Cytokines: Soluble glycoproteins secreted by immune system cells that modulate immune and inflammatory responses. They are divided into two broad categories: pro- and anti-inflammatory cytokines. Pro-inflammatory cytokines, including tumour necrosis factor (TNF), interleukin 1 (IL-1), interleukin 2 (IL-2), and interferon gamma (IFN-g), are associated with the T-helper type 1 (Th1) cell subclass, and upregulate cell mediated inflammatory responses. Anti-inflammatory cytokines include transforming growth factor beta (TGFb), interferons alpha (IFNa) and beta (IFNb) and interleukin-10 (IL-10). Interleukin 4 (IL-4), associated with the T-helper type 2 (Th2) subclass is involved in allergic inflammation, but downregulates cell-mediated immune responses. Cytokines play an important role in MS, based on studies of both the EAE animal model and human disease. The pro-inflammatory cytokines are considered to induce or worsen disease features in MS. In contrast, anti-inflammatory cytokines are thought to be protective and to ameliorate disease features in MS.

They direct/cause the MMPs to do lots of MS damage but that is another posting.

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Old 10-04-2008, 11:54 PM #4
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I just noticed my vision is dim tonight. I hope that's not the harbinger of doom that the insomnia has probably been a warning of.
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Old 10-05-2008, 12:14 AM #5
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Default shrinkage not doom

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I just noticed my vision is dim tonight. I hope that's not the harbinger of doom that the insomnia has probably been a warning of.
Yep. Vision is the second thing to go. Insomnia can also contribute to brain shrinkage. See my last MRI below. Radioligist said;
Quote:
moderate brain shrinkage noted but appropriate for age and medical condition
.

jackD


Last edited by jackD; 10-05-2008 at 02:08 AM.
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