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Study: Red Wine Extract Makes Fat Mice Healthy Again

Thursday, November 02, 2006

WASHINGTON — Obese mice on a high-fat diet got the benefits of being thin — living healthier, longer lives — without the pain of dieting when they consumed huge doses of red wine extract, according to a landmark new study.

It's far too early to know if this would work in people, scientists said. But several were excited by the findings, calling it promising and even "spectacular."

The study by the Harvard Medical School and the National Institute on Aging shows that heavy doses of the red wine ingredient, resveratrol, lowers the rate of diabetes, liver problems and other fat-related ill effects in obese mice.

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Fat-related deaths dropped 31 percent for obese mice on the supplement, compared to fat mice that got no treatment. The mice that got the wine extract also lived longer than expected, the study showed.

And astoundingly, the organs of the treated fat mice looked normal when they shouldn't have, said study lead author Dr. David Sinclair of Harvard Medical School.

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