So glad your biopsy was benign, Lady. It's so stressful to wait and worry.

I usually wake up sometime between 12:30 AM and 2 AM - depending on which cat decides they've waited long enough on me! I try to wait till just before I go back to bed to take my LDN.....waiting as late as I can. Sometimes I'm just too sleepy and take it at 1 AM. Sometimes I can hold out till closer to 3 AM. I can't really tell a big difference regardless of whether I take it early or later.

I have noticed that my right hand is getting more "feeling" back in it, though. It's still numb for the most part but I have more sensation in it and can tell when I'm holding something whereas before I couldn't tell if I was holding anything at all.