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04-10-2009, 10:44 AM | #1 | |||
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Statin Therapy Inhibits Remyelination in the Central Nervous System
http://ajp.amjpathol.org/cgi/content....2009.080947v1 Am J Pathol. 2009 Apr 6. Statin Therapy Inhibits Remyelination in the Central Nervous System. Miron VE, Zehntner SP, Kuhlmann T, Ludwin SK, Owens T, Kennedy TE, Bedell BJ, Antel JP. Our findings suggest that simvastatin inhibits central nervous system remyelination by blocking progenitor differentiation, indicating the need to monitor effects of systemic immunotherapies that can access the central nervous system on brain tissue-repair processes. __________________
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04-10-2009, 10:58 AM | #2 | |||
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Wisest Elder Ever
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In plainer English (which I needed myself to understand the seriousness of this report)
http://bloodbrainbarrierblog.blogspo...elination.html Quote:
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei ************************************ . Weezie looking at petunias 8.25.2017 **************************** These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.
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04-10-2009, 11:41 AM | #3 | |||
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Grand Magnate
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Great -- I have been taking it for several years. It has lowered my cholesterol.
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04-10-2009, 01:02 PM | #4 | ||
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Quote:
Linda |
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04-10-2009, 09:39 PM | #5 | |||
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Magnate
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My father's been on statins for quite a long time now, and constantly complains about them because of the side effects they can cause. He swears by CoQ10.
Thanks for the information, I'll have to share it with Dad (who has heart troubles, not MS, but it'll be a common point of interest for us).
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2004 to present - Trigeminal Neuralgia 2007 to present - Burning Mouth Syndrome March 2008 - Multiple Sclerosis DX 05/2008 - Relapse 05/2008 to 02/2009 - Copaxone 10/2011 - Relapse - Optic Neuritis developed 9/2012 - Relapse - Balance issues 1 sided 8/2012 - Erythema Nodosum - diagnosed 10/2012, reaction to Topiramate (Topamax) April 7/14 - Raynaud's Syndrome DX |
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04-13-2009, 01:16 PM | #6 | ||
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New Member
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Hi--I'm glad our humble little blog is generating discussion, but I feel (based on some comments I've read) that I need to emphasize the following:
I am NOT a physician (I'm a scientist), and NOTHING I write on the BBB Blog should in any way be construed as medical advice. PLEASE do not make any changes to the medications you are taking without consulting your physician first. Many thanks, and best wishes, Brian Hawkins, PhD [QUOTE=mrsD;493965]In plainer English (which I needed myself to understand the seriousness of this report) |
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04-13-2009, 02:39 PM | #7 | |||
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Wisest Elder Ever
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Quote:
Quote:
Everyone here mostly checks with their doctor. What is concerning about the newest statin information for the readers of the MS forum, is that high dose statins were touted by the drug companies as a TREATMENT for MS. And it looks like this is not going to work or be good for them. If you cruise around, you'll find olsen and myself putting up all the data coming out about statins, not just the positive ones, we get in the general media. I think doctors have been kept in the dark about the damage potential statins have, and therefore cannot answer questions adequately when patients ask them. Providing that data here gives them a chance to print it out and take it with them to the doctor. In that case it is a roundabout way of providing CME for those doctors! And I agree with you...that the newest attempt to suggest use of statins for children is deporable! It is right up there with atypical antipsychotics for toddlers! (and we know where that has gone) We have a warning on every page of these forums to consult your doctor, before trying any suggestions that appear here. And I always put up carefully checked medical information, to support my posts as well. Thanks for chiming in.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei ************************************ . Weezie looking at petunias 8.25.2017 **************************** These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.
Last edited by mrsD; 04-13-2009 at 03:03 PM. |
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04-16-2009, 11:36 AM | #8 | |||
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WHAT!?
Stupid drugs with their stupid side effects. I need to read up on more alternative meds for MS. Homeopathic, I think it's called. My first neuro put me on simvistatin shortly after I was dx. My level was 223, whereas 2 years prior it was at 175. When I quizzed him on how the jump occurred with no real change in my diet, he said the demyelazation (or however it's spelled) dumps the fat stripped off the nerves as cholesterol into our bloodstream. I haven't been doing any real research of my own on MS lately. That stops today because; I am the MonSter that MS fears. Wait. I realize I'm overreacting. But does the body really replace that stuff that's been stripped off? If so, how could this disease even exist? I have so much reading to do.
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04-16-2009, 01:29 PM | #9 | |||
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Grand Magnate
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For now, I plan on staying on simivastatin, but do plan on asking my neuro his thoughts about the article. My dosage is fairly low, and it has helped reduce my cholesterol. It is just one study -- correct?
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04-17-2009, 12:32 AM | #10 | |||
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Member
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Quote:
But don't tell anyone.
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You can't have everything. Where would you put it? -Steven Wright Once you change your mind, you can change your life. -Della Reese . Always outnumbered... Never outgunned . *I* am the MonSter that MS fears |
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