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Statin Therapy Inhibits Remyelination in the Central Nervous System

 
 
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Old 04-10-2009, 10:44 AM #1
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Default Statin Therapy Inhibits Remyelination in the Central Nervous System
Statin Therapy Inhibits Remyelination in the Central Nervous System


http://ajp.amjpathol.org/cgi/content....2009.080947v1

Am J Pathol. 2009 Apr 6.
Statin Therapy Inhibits Remyelination in the Central Nervous System. Miron VE, Zehntner SP, Kuhlmann T, Ludwin SK, Owens T, Kennedy TE, Bedell BJ, Antel JP.
Our findings suggest that simvastatin inhibits central nervous system remyelination by blocking progenitor differentiation, indicating the need to monitor effects of systemic immunotherapies that can access the central nervous system on brain tissue-repair processes.
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