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Tysabri Information and Check In part 2

 
 
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Old 05-14-2009, 10:43 PM #11
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Natalie8 Natalie8 is offline
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Natalie8 Natalie8 is offline
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Join Date: Apr 2008
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Default statistics on PML and Tysabri
According to the VP of Drug Safety at Biogen the chance of getting PML on Tysabri are lower than initially suspected based on the clinical trials. Maybe someone posted this article already.

http://www.medscape.com/viewarticle/702373

The incidence of PML in patients taking natalizumab for 1 year or more is 2.4 per 10,000 patients, 1.4 per 10,000 in patients treated for 18 months or more, and 3 per 10,000 in patients treated for 2 years or more, with confidence intervals "that are overlapping," said Dr. Bozic.

I'm not sure what "confidence intervals overlapping" means.
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