Of course the manufacturer is going to advise you to take a full dose. The more you use the more you have to refill!

Like Cherie said.......it's just a crap shoot. It might work. It might not. I just got tired of being a guinea pig for big pharma.

Good post, my twin sistah of a different mother!

I'm on the other side of the coin, with a very high tolerance for side effects and that stuff. I had lots of practice in my younger years with recreational "pursuits". For the most part, I don't have side effects. I watch for them, but nothing happens-USUALLY!

I cannot take flexeril. It leaves me drooling on the couch even at a very low dose, not that that side effect is a bad thing at certain times, like when you have been struggling with pain and agony for a lengthy period of time. I just don't want to be that way every time I take a pill. I have none of the reactions that others report with baclofen. I never did. I even questioned whether it was working, until the first time I tried to skip it completely. It works, and works well for me when I need it to.

The drug companies use a dose that has proved to work well across the spectrum of patients trialed. It does not mean it's the correct dose for everyone and there will always be people with a more noted reaction than others. I think I am just lucky that I am at the tolerant end.

Just choked on my water on this one. Long story short, when the neuro and I decided meds were not going to be the route for the spasticity for me she sent me to PT. The PT was young and just out of college. I was explaining my experience with the meds and told her that as a child of the 60's and 70's I apparently didn't do enough drugs. Couldn't tolerate it. LOL

Definitely as interesting point tkrik. Just how do they know?

We could have a 250 lb man taking "C" and a 125 lb women. Is the fat level the same for injection distribution purposes?

Or what about one who metabolizes an oral drug quickly, and maybe one who absorbs drugs slowly. The ideas on this are endless.
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Speaking of "C", there is a new clinical trial on "C". It will consist of two different formulations. Maybe pain and injection site reactions will be stopped.

Safety of New Formulation of Glatiramer Acetate (Song)

Purpose

The purpose of this study is to compare injection-site reactions and pain associated with injections of the approved formulation of Glatiramer Acetate (GA) versus investigational formulation of GA. In addition, the investigators will evaluate the side effects of the two formulations of GA.

Study Start Date: July 2009
Estimated Study Completion Date: November 2009
Estimated Primary Completion Date: November 2009 (Final data collection date for primary outcome measure)

http://www.clinicaltrials.gov/ct2/sh...s=teva&rank=15