Lately I have been having alot of short term memory loss and when I am talking , all of a sudden I can't remember what the next word was I was going to say., things like I put something and used the same thing for years, now when I go to find it , it is in the same place but doesn't look like it did before to me, so I think it is not the same thing............wrong , but it is., anyone else have this? I take 10 mg of prednisone eod., thats it for now, but my ocular problems are worse so I have to call my neuro.

All the time.
Tony

mine is worst when my mestinon is wearing off. at the higher doses, I see more of a difference. I know they say it does not cross blood/brain barrier, but I am not buying it. Wondering if anyone has done brain studies on MG patients to see if the AchR there are impacted as well.....

answering myself:

These guys http://www.ionchannels.org/showabstr...?pmid=10561522 say not enough antibodies found in CSF for it to be immune, but make very good points about lack of sleep. I know lately sleep has almost as much impact as meds on my condition.
If u have trouble eating, could also be B12 problems

however, this one http://www.sciencedirect.com/science...f&searchtype=a seems to indicate that there are muscarinic antibodies involved in some cases.

Like everything else with this disease.. it probably varies from sub type to subtype.

I have trouble remembering words. The odd thing is that I feel just fine until I try to talk. Then if feels as if something happens to block the word I intended to say. I think my problem has something to do with stress because if I can relax I can remember the words. This is a complicated issue, but I do know this forgetting word problem started with MG. I get plenty of wonderful sleep, seems to be the only thing I can do well, so I don't think my memory problem is from lack of sleep. The word forgetting happens most when my MG symptoms are worst and towards the end of the day.

The B12 vitamins help somewhat with the memory problems for me.

I SOOOOOOOOOOOO suffer from short term memory loss and word finding! In fact, for me, it was the first thing I noticed 4 years ago because I have always had a STELLAR memory of even THE most minute details! I also had a WONDERFUL vocabulary with a love for words as I've been an avid book reader since before I could even read! Now, I struggle to remember things, I lose my words mid sentence (if I'm fortunate enough to be able to know which words I want) and.... see...... I just did it. lol!! Oh another problem I have is getting the words OUT. Sometimes I'll be talking, and say I wanted to say the word 'open'.... I'll start with the "o" then the rest of the word get's stuck. I can't explain it very well.

I'm not glad that I'm reading of others having this problem, but I'm glad to know there ARE because in all I read of MG, this is NOT included, but it's VERY much a miserable presence in my daily life.

I so hate that feeling of not being able to retrieve a word. it is not like I forget it, it is more like the word has been completely erased from my stored vocabulary. I can visualize exactly where it should be coming from and there is a huge blank space. If I look up the word , I can sometimes make it stick again.

YaYa, I so sympathize. I used to have a huge vocabulary, tonight at dinner I could not remember the word agile to save my soul. My B12 tested fine, but I am considering supplementing anyway.

This happens to me so frequently as well. You know the word , but it's stuck somewhere in a spot you can't quite get to!! I also find I can't always remember how to spell something. I never, never had trouble spelling, I was always the person people asked when THEY couldn't spell something. I now keep a dictionary handy, especially when a write in my journal...I so hate spelling errors. My sister frequently fills in the "blanks" for me!

I got sick in the middle of June they ran the usual scans, labs and such. At that time the only thing that seemed to be causing my problems was a B12 deficiency. I was started on a series of injections and oral meds. This helped some but didn't resolve the problem totally. The neuro I saw at the hospital started testing me for MG at my first F/U visit. I still take a B12 supplement daily, also an injection monthly.

The United States has one of the widest B12 normal ranges in the world. If the US used other countries ranges more people in the US would have B12 issues. In other countries they also supplement on a greater level than here. Many doctors use B12 injections as a routine thing, not so much in the US today...although this was very popular in the "old" days.

Rachel

This is going to sound strange but have you tried eating fish a two or three times a week or taking fish oil capsules? It really is a super brain food. So is chlorella.

Those who are on Pred or other immunosuppressants need very good omega 3's, etc. to counteract the effects of them. Pred is an antiprostaglandin, meaning it reduces both good and bad prostaglandins. To get good ones back, you need to eat or supplement with them!!!

Or try sublingual B12 or get your thyroid checked or cortisol or a sleep study or lots of other things that could cause brain fog. Don't assume it's the MG. It could be but it could be a boatload of other things too.

I feel so awesome after eating fish (without mercury). And it is great for acne too.

I hope you can get back some of your brain power!

Annie

Annie, I'm already on a B12 regimine, thyroid gets checked regularly. Only on Mestinon at this point. Never gave much thought to the other things though. I'm so not a fish person, I only like tuna & shrimp. I was considering a fish oil supplement but the thought of a "fishy" aftertaste turned me off. I know there are new types on the market now so I guess I'll have to add them to my "medication box"

Thanks again for all your input!
Rachel