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New here with peripheral neuropathy / unknown cause

 
 
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Old 11-20-2009, 08:53 AM #4
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mrsD mrsD is offline
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Welcome to NT... I am sorry you have this new symptom to deal with.

Allopurinol is on the list of drugs that can cause PN.

Quote:
Eur Neurol. 1993;33(3):193-4.
Regression of allopurinol-induced peripheral neuropathy after drug withdrawal.

Azulay JP, Blin O, Valentin P, Abegg P, Pellissier JF, Serratrice G.

Clinique des Maladies du Système Nerveux, CHU Timone, Marseille, France.

A patient experienced an axonomyelinic peripheral neuropathy during a long-term allopurinol treatment. The symptoms and signs regressed after drug withdrawal, and the nerve conduction velocities and distal latencies improved. The incidence of allopurinol-induced peripheral neuropathy is very low. Thus, facilitatory factors have to be sought.

PMID: 8385614 [PubMed - indexed for MEDLINE]
from http://www.ncbi.nlm.nih.gov/pubmed/8...m&ordinalpos=8

Allopurinol is not used as much now as in the past. So therefore not many people would be in the pool, to report serious issues.

The only way to test the PN link is to stop the drug for a while.
Please discuss this with your doctor, before doing it yourself.
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