Originally Posted by en bloc

Hi and Welcome to Neurotalk.

I don't know how much I can help, but your symptoms certainly sound familiar in some ways.

First let me ask a few questions:

What are the doctors saying at this point...or is candida the only diagnosis?

Please give some background in regards to other testing and current medications.

Have you been worked up for autoimmune disease or diabetes insipidus?

Do these episodes occur daily, hourly or just come in waves here & there without a schedule?

Tell me more about the frequent urination. Is the urine overly dilute? Are you drinking large amounts of water? Have you been getting dehydrated from all the urination (urine turns dark)?

The first thing to jump out at me is the frequent urination. Has your blood sugar been checked during these episodes? Diabetes causes frequent urination (hence the origin of the word). However, there is also diabetes insipidus (not related to sugar diabetes) which also causes frequent urination. It can be associated (most commonly) with pituitary issues and the lack of ADH (anti-diuretic hormone).

Your cortisol level is strange (backward). I would assume they did an MRI with a pituitary protocol to properly look for an adenoma as well. I don't know much about the partially empty sella, but certainly they would have checked pituitary function via blood tests to make sure you are producing proper levels of hormones for various things.

There is also the low BP and other symptoms that are of concern. Are you weak when you stand up? Have you checked your BP upon standing to see if it drops? You may have some autonomic dysfunction going on. Neurogenic bladder (which can also cause frequent urination) can occur with autonomic neuropathy as can the low BP, visual disturbances, temperature deregulation, and other symptoms.

There are several conditions that cause the variety of symptoms you list. Autoimmune conditions like Sjogren's can cause dry mouth, eyes, lack of sweating, fatigue, AND can include neuro complications like autonomic dysfunction (and related symptoms I mentioned above).

The diabetes insipidus can throw off all kinds of labs due to the electrolyte changes after urinating excessively.

Honestly, you should be worked up for both of these if you haven't already.

Is there anything that preceded these episodes...another illness, trauma/injury, medication? What was the antibiotic you mentioned? Was this from 12 years ago when things began or something more recent?

The more info you provide, the better.