I've been on NeuPro 8mg for almost a year with fantastic success. However, in spite of following the recommendations for rotating application sites, my skin is revolting and it's becoming more difficult to tolerate the patches strictly from a dermatological perspective.

I spoke with my neurologist (MDS) and they recommended I try extended release ropinerole at the equivalent dose of 8mg, no tapering down of NeuPro or ramping up of ropinerole needed - just take off the patch and pop a pill (the half life of rotigotine is about 5 hours).

I have attempted this switch 4 different times now, each resulting in severe insomnia and restlessness to the point that I couldn't tolerate the switch for more than 2 (sleepless) days. I put a NeuPro patch on and was back to normal (and fast asleep) within 4 to 6 hours. I never experienced any nausea or adverse events other than total sleeplessness and moderate restlessness (perhaps two sides of the same coin). In one attempt I even waited 12 hours after taking off the patch before taking the ropinerole XL - no difference.

Anybody have any experience switching from NeuPro to ropinerole (Requip), good or bad, that you'd like to share?

DRHiggins,

It is great to have you come and be with us. You will fine a great number of dear friends to listen when you are in need of ears. Please, just let us know how we can help you out. You will find out we are supportive and relaxing place.

Please keep us up to date on your situation. Again welcome, looking forward to seeing you around. My thoughts and prayers are with you.

Darlene