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The standard complement was preformed each time and was normal.

Joint pain is consuming, my thumb now has bone on bone OA. In an effort for pain relief I recently visited a physical therapist a few times. They can't help with bone on bone, but his initial evaluation did show peripheral neuropathy in both arms.

My mother has RA. My son is insanely hypermoblie. My nephew was clinical diagnosed with Charcot-Marie-Tooth at around 13, he is now 23 and becoming symptomatic. My father is totally disabled with peripheral neuropathy, with a presumptive diagnosis of CMT. I fall frequently, as do my father and sister. My sister has an aneurism near her brain stem which is being watched, but treatment avoided because at this point it is too dangerous to treat unless it grows.

I have significant hypermobility in many joints and was tested for vEDS, which was negative. No other tests along the re EDS were preformed.

While the first tests were conducted I was losing weight at an alarming rate, desperately fatigued with chronic diarrhea. When it became clear there was a medical solution wasn't on the horizon, I explored Alternative and Complementary 101. The first thing was to attempt to restore lost nutrients in transdermally wherever possible. Then I added food based vitamins gradually, and felt some improvement. And began to regain the weight.

Just when I thought there was a light at the end of the tunnel, it all started again. The PCP did another ANA, it was high, the complements normal. Diagnosis: I'm malingering and obsessed (unspoken but understood).

What I don't understand is that physicians uniformly ignore positive results, while using negative results as a basis for diagnosis. Objective diagnostics are insignificant.