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Old 02-06-2008, 10:10 AM #1
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Default statins and memory

article to consider:


Barres and Smith's in vitro findings of importance of brain cholesterol (recalling that fat soluble statins cross the BBB) synopsis: www.sciencemag.org
Neurons need cholesterol secreted by glial cells to form and maintain functional synapses. In addition to synaptogenesis, cholesterol is probably responsible for production and transport of vesicles necessary for neurotransmission. If one accepts the concept of neuronal plasticity in the adult brain, then deliberately
suppressing cholesterol metabolism in the brain seems more than questionable.
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Old 02-06-2008, 01:46 PM #2
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Flash1,

One big, warm, tight, hug, handshake and howdy, moose-size official type welcom to the site. This place is amazing!
Thanks so much for bringing this up and sharing your perspective, as well as everyone who responded.

My cholesterol was in the 170s until I was dx with MS. It then shot up to the 230s in just a year, with no change in diet. (My neuro explained that the demyelating process was dumping the fatty tissue into veins as cholesterol). I was put on Simivistatin. (SP)

Now my memory has never been as strong as wanted, but I chalked it up to being a worthless drunk for so many years. And more recently, the concussion in a car wreck from 2 years ago. Now at least I have another culprit to the cause.
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