Almost 15 years come and gone. Know anyone who tried "ferriascorbate"?


1. Gerontology. 1987;33(3-4):168-71.

Dopamine action and disorders of neurotransmitter balance.

Birkmayer W, Birkmayer JD.

Evangelic Hospital, Vienna, Austria.

Disorders of neurotransmitter balance are observed in Parkinson's disease,
pharmacotoxic psychosis and depression. The dopamine-serotonin ratio is reduced
to about 20% in Parkinson and pharmacotoxic patients in the caudate nucleus and
in the substantia nigra. The serotonin content in these brain areas is lowered
only to about 50% in comparison to that of the control, whereas the dopamine
level is reduced to 85% in Parkinson patients. This dopamine deficiency has been
substituted by exogenous supply of L-dopa in combination with decarboxylase and
monoaminooxydase inhibitors. First evidence is presented that L-dopa can be
replaced, at least partially, by iron in form of a ferriascorbate complex. This
iron compound improves the symptoms of Parkinson's disease to almost the same
extent as L-dopa.


PMID: 3653699 [PubMed - indexed for MEDLINE]