A number of posters have mentioned that they don't feel "off" or "on" in response to the presence or absence of their medication. Others mention that they feel "on" within an hour or so of taking their medication and they feel the "off" signal when the medication has run it's course. I am in the former group. I don't feel anything after taking my medication. On the other hand, I don't feel anything after the medication has run it's course and I'm due for a refill (I'm on STALEVO and I take it every three and a half hours). To those who have "Offs" and "Ons" what does it feel like? Am I missing something?

All the best,

Lloyd